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The 13th Annual Neuroscience Research Day

March 5, 2004

w/ a special seminar

by Dr. Christine Holt:

" How Axons Navigate From the Eye to the Brain"

 

   

 

Schedule of Events:

11:00 AM - 4:00 PM

Posters will be presented in front of the Lois Pope LIFE Center. Presenters will be present from 2:00 PM until 3:30 PM. In the event of rain, the posters will be held inside the Lois Pope LIFE Center. For a complete listing of poster titles, click here
.

 

4:00 PM

Special seminar in Mailman Center, 8th Floor Auditorium, University of Miami School of Medicine Campus. Keynote Speaker, Dr. Christine Holt from Cambridge University:

*** How Axons Navigate From the Eye to the Brain ***

5:30 PM - 7:30 PM

Terrace reception on Lois Pope LIFE Center Balcony
.

 

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Poster Session Titles:

Alphabetical by Author
A-B | C-D | E-J | K-M | N-Q | R-T | U-Z


Achat-Mendes C, Anderson K, Itzhak Y. “Opposing consequences of amphetamines-induced dopaminergic and serotinergic neurotoxicity on reward-seeking behavior in mice”. Neuroscience Graduate Program, Department of Psychiatry & Behavioral Sciences.

Bacman S, Kirkinezos I, Hernandez D, Moraes CT. “A Model for the Pathogenic Mechanism of Mutated SOD1 in ALS”. Dept of Neurology, Dept of Cell Biology & Anatomy.

Beekhuizen K. “Effects of Massed Practice and Somatosensory Stimulation in Individuals with Incomplete Spinal Cord Injury”. Miami Project.

Bent M, Grumbles RM, Rudinsky M, Sesodia S, Castella GTB, Thomas CK. “Effects of Neurotrophic factor delivery to muscle on axon regeneration from embryonic neurons transplanted into adult rat peripheral nerve”. Miami Project, Dept of Neurological Surgery.

Berrocal YA, Pearse DD, Andrade CM, Gomez-Marin O, Bartlett Bunge M, Eaton MJ. “Evaluation of the sensory system in a commonly used contusive spinal cord injury (SCI) model for assessment of regenerative cellular therapies”. Miami Project, Dept of Neurological Surgery, Dept of Cell Biology & Anatomy, Dept of Epidemiology & Public Health, VA RR & D Center of Excellence in Functional Recovery in Chronic Spinal Cord Injury, VAMC.

Bracchi-Ricard V, Brambilla R, Karmally S, Walters WM, Hu WH, Green EJ, Bethea JR. “NF-kB is an Important Regulator of Learning and Memory and Synaptic Plasticity”. Miami Project, Dept of Psychology.

Brelidze TI, Magleby KL. “Probing the Intracellular Vestibule of BK Channels Using K+ Flux Near the Diffusion Limit and Different Size Sugars”. Dept. of Physiology & Biophysics.

Brown KM, Field-Fote EC. “Low frequency depression of the soleus H-reflex is absent in standing”. Motor Rehabilitation Laboratory, Miami Project.

Buchser WJ, Lu J, Xu Z. “Frequency Response of Saccular afferents in a Teleost Fish”. Neuroscience Graduate Program, Dept of Biology.

Bunge, MB, Pressman, Y, Bates ML, Garg MD, Wood PM, Pearse DD. “Continuous cyclic amp elevation by membrane permeable derivatives and phosphodiesterase inhibition act additively to increase myelination in DRGN-SCHWANN CELL CULTURES”. Miami Project, Dept of Cell Biology and Anatomy, Dept of Neurological Surgery.

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Chaverneff FT, Panickar KS, Barrett JN. “Neurotrophins facilitate nuclear translocation of SMADS in septal neurons in response to bone morphogenetic protein 7”. Neuroscience Graduate Program, Dept. of Physiology & Biophysics.

Cheng L, Itoh K, Lemmon V. “Abnormal brain development in L1-6D mutant mice”. Miami Project, Neuroscience Center.

Corredor R. “A primate spinal cord injury model of olfactory ensheathing glia and Schwann cell autotransplantation”. Miami Project.

Dave KR, Bradley WG, Pérez-Pinzón. “Aberrant dPKC activation in spinal cord of Wobbler mouse: a model of motor neuron disease”. Dept of Neurology.

Diaz F, Garcia S, Moraes C. “A Mouse Model of Cytochrome c Oxidase Deficiency in Central Nervous System”. Dept. of Neurology, Dept. of Cell Biology & Anatomy.

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Eaton MJ. “Human neuronal cell lines for the treatment of pain and spasticity following SCI”. VA RR&D Center of Excellence in Functional Recovery in Chronic Spinal Cord Injury, Miami VAMC, Miami Project, Dept of Neurological Surgery.

Everhart D, Reiller E, Mirzoian A, McIntosh JM, Malhotra A, Luetje CW. “Identification of residues that confer a-conotoxin-pnia sensitivity on the a3 subunit of neuronal nicotinic acetylcholine receptors”. Dept of Molecular & Cellular Pharmacology, Neuroscience Graduate Program, Dept of Biochemistry & Molecular Biology, Dept of Biology & Psychiatry-Univ of Utah Salt Lake City.

Furmanski O, Lee JW, Huang J, Sagen J. “Promoting Gaba-ergic differentiation of rat embryonic telencephalic precursor cells in vitro”. Miami Prjoect, Neuroscience Graduate Program.

Gonzalez-Brito M, Bixby JL. “Expression of a Novel Full Length Protein Tyrosine Phosphatase Delta Isoform”. Dept of Pharmacology, Neuroscience Program, Miami Project.

Guest J. “A primate spinal cord injury model to study olfactory ensheathing glia and Schwann cell autotransplantation”. Dept. of Neurological Surgery.

Gwadry F, French-Mullen JMH, Pablo JP, Mash DC. “Cocaine modulates the expression of a diverse set of genes in human hippocampus”. Gene Logic, Inc. Gaithersburg MD, Dept. Neurology.

Hackman JC, Holohean AM. “Carbonic anhydrase inhibitors reduce GABA-induced motoneuron depolarizations in the frog spinal cord”. Spinal Cord Pharmacology Laboratory-VA Medical Center, Dept of Neurology, Dept of Physiology & Biophysics.

Hsiao B, Magleby KL, Luetje CW. “Zinc potentiates neuronal nicotinic receptors by increasing open probability”. Dept of Molecular & Cellular Pharmacology, Dept of Phsyiology & Biophysics.

Jayakumar AR, Rama Rao KV, Norenberg MD. “Glutamine-induced free radical generation in neural cells”. Dept of Pathology, Dept of Biochemistry & Molecular Biology, VA Medical Center.

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Kimbell LM, Ohno K, Engel AG, Rotundo RL. “The heparin binding domain of the acetylcholinesterase collagenic tail is necessary but not sufficient for localizing the enzyme to the neuromulscular junction”. Dept of Cell Biology & Anatomy, Mayo Medical School-Rochester MN.

Klein CS, Hager-Ross CK, Thomas CK. “Thenar motor unit contractile properties after human cervical spinal cord injury”. Miami Project, Dept of Neurological Surgery.

Lee S, Lemmon V. “Cadherins and development: CDH23 in the retina”. Miami Project, Neuroscience Center.

Liu CL, Hu BR. “Pathogenesis of Neuroanl Death after Hypoxia-Ischemia Changes During Brain Development”. Dept of Neurology.

Liu CL, Martone ME, Hu BR. “Ischemic Preconditioning Prevents Protein Aggregation after Transient Cerebral Ischemia”. Cerebral Vascular Disease Research Center, Dept of Neurology.

Lu J, Xu Z, Buchser WJ. “Coding of Acoustic Particle Motion by Utricular Afferents in a Teleost Fish”. Dept of Biology, Neuroscience Graduate Program.

Mash DC, Qin Y, Ouyang Q, Pablo JP, Basile MJ. “Cocaine abuse triggers abnormal expression of alpha-synuclein”. Dept. of Neurology.

McCullum MH, Liang JS, Potter LT. “Confocal studies of hippocampal dendritic spines rich in M1 muscarinic receptors”. Dept of Molecular & Cellular Pharmacology.

Mendes SW, Liebl DJ. “Corpus Callosum Axon Guidance: The Role of Ephrins and Eph Receptors”. Dept. of Neurology, Neuroscience Graduate Program.

Mihalak K, Hsiao G, Everhart D, Mederos A, Malhotra A, Luetje CW. “Probing the zinc potentiation site on neuronal nicotinic receptors with the substituted-cysteine accessibility method”. Dept of Molecular & Cellular Pharmacology, Dept of Biochemistry & Molecular Biology.

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Neary JT, Kang Y. “Purinergic signaling and cell cycle regulation in astrocytes”. Research Service, Miami VA Medical Center, Dept of Pahtology, Dept of Biochemistry & Molecular Biology, Neuroscience Program.

Neary JT, Kang Y. “Role of ATP/P2 receptors in the activation of astrocytic protein kinase B/AKT by traumatic brain injury”. Research Service, Miami VA Medical Center, Dept of Pathology, Dept of Biochemistry & Molecular Biology, Neuroscience Program.

Noga B. “Pattern of Monoamine Release Produced by Raphe Magnus Stimulation”. Miami Project.

Nonner W, Peyser A, Gillespie D, Eisenberg B. “Moving Gating Charges: Comparing Electrostatic Energetics of the S4 Motion of Different Models Topic Categories: 5C Voltage-gated K Channels; 9F Theory”. Dept of Physiology & Biophsyics, Neuroscience Graduate Program, Molecular Biophysics and Physiology-Rush Medical College.

Pardinas JR, Lemmon V. “Gene Expression in Regeneration: PNS RAGs”. Miami Project.

Paredes J, Levine J, Schneiderman N, McCabe, PM. “Chronic microdialysis of CNS peptides as a function of social environment in the WHHL rabbit”. Dept of Psychology-University of Miami, Dept of Physiology & Neurobiology-Northwestern University, Evanston IL.

Pérez-Pinzón MA, Raval AP, Dave KR, Lange-Asschenfeldt CH. “Dual role of protein kinase C isozymes in neuronal neuroprotection/pathology following ischemia”. Dept of Neurology and Neuroscience, Cerebral Vascular Disease Center.

Pinzon A, Marcillo A, Bartlett Bunge M, Dietrich, WD. “Evaluation of Erythropoietin as a neuroprotective agent in rat spinal cord contusion and compression models”. Replication Studies Group, The Miami Project.

Qian X, Butler A, Salkoff L, Magleby K. “Sodium-Activated K+ channels are also Calcium-Activated K+ Channels”. Dept of Physiology & Biophysics, Anatomy & Neurobiology-Washington Univ School of Medicine St. Louis MO.

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Rama Rao KV, Norenberg MD. “Manganese induces the mitochondrial permeability transition in cultured astrocytes”. VAMed Center, Dept of Pathology, Dept of Biochemistry & Molecular Biology.

Ricard J, Salinas J, Liebl D. “EphrinB3 controls proliferation in the adult subventricular zone”. Miami Project.

Ruiz CA, Rossi SG, Randall WR, Rotundo RL. “Regulated expression of acetylcholinesterase collagenic tail messenger RNA by muscle activity controls assembly of the synaptic enzyme form”. Dept of Cell Biology & Anatomy, Dept of Pharmacology & Experimental Therapeutics-Univ of Maryland School of Medicine Baltimore MD.

Smith R, Lemmon V. “Spatio-temporal dynamics of L1CAM Signaling”. Neuroscience Gradaute Program, Miami Project.

Takeda Y, Ginsberg MD, Sick TJ. “Dynamic changes of mitochondrial membrane potential and DC potential in vivo during focal ischemia”. Dept. of Neurology, Anesthesiology-Okayama Univ Med School, Japan.

Tomchik SM, Lu J. “Organization of the Medullary Octavolateral Nuclei in a Teleost Fish”. Dept. of Biology.

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Usher L, Lemmon V, Bixby JL. “Screening Chemical Libraries for Compounds that Promote Nerve Regeneration”. Miami Project, Neuroscience Center, Dept of Molecular & Cellular Pharmacology, Neuroscience Graduate Program.

Wanner IB, Tran M, Neary JT. “Regulation of N-cadherin by extracellular ATP and mechanical strain by astrocytes – implications for glial networks”. Miami Project, Veterans Affairs Medical Center, Dept. of Pathology, Dept. of Biochemistry and Molecular Biology.

White L, Wood P, Bartlett Bunge M, Fregien N. “The levels of heregulin receptors HER2 and HER3 are post-transcriptionally increased in human Schwann cells by treatment with forskolin or dibutyryl-cyclic AMP". Miami Project, Dept. of Neurosurgery, Dept. of Cell Biology and Anatomy.

White L, Wood P, Bartlett Bunge M, Fregien N. “The levels of heregulin receptors HER2 and HER3 are post-transcriptionally increased in human Schwann cells by treatment with forskolin or dibutrylcyclic AMP”. Dept of Neurosurgery, Dept of Cell Biology & Anatomy.

White MG, Saleh O, Nonner D, Barrett JN. “Mechanisms of heat stress-induced striatal neuron apoptosis”. Dept. of Physiology & Biophysics, Neuroscience Graduate Program.

Zhang Y, Niu X, Brelidze TI, Magleby KL. “Differential Effect of the Ring of Negative Charge on Block of BK Channels by Md2+ and Polyamines”. Dept of Physiology & Biophysics.

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Location:

Poster Presentation : 11:00am-4:00

University of Miami School of Medicine, Lois Pope LIFE Center, Research Quadrangle (outside)

 

Special Seminar: 4:00pm~5:00pm

University of Miami School of Medicine, Mailman Center, 8th Floor Auditorium

 

Reception: 5:30pm~7:00pm

University of Miami School of Medicine, Lois Pope LIFE Center, Balcony

 


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Dr. Christine Holt:

Dr. Christine Holt is a world leader in the study of axon guidance during embryonic development. Her lab has made important contributions in this area for 20 years, focusing on the navigation of retinal ganglion cell axons in the developing vertebrate visual system. Dr. Holt and her colleagues were pioneers in the use of in vivo imaging to examine axon guidance decisions made by developing growth cones. They have made key observations concerning the molecular basis of guidance decisions at navigational “choice points”. As examples, Dr. Holt’s lab discovered that ephrin B is important in regulating the routing of retinal axons at the optic chiasm, and that netrin/DCC/laminin interactions are critical in directing axons out of the eye. Their recent experiments have shown that local protein synthesis and proteosomal degradation are required for the chemotropic responses of retinal ganglion cell growth cones and are involved in neuronal regeneration. This work is at the forefront of the axon guidance field.

Dr. Holt received a BSc degree from Sussex University, and a PhD in Zoology from King’s College, London, working with John Scholes. After postdoctoral work with Bill Harris and Colin Blakemore, she took a faculty position at UCSD in 1985. Dr. Holt rose through the ranks at UCSD, becoming a tenured Associate Professor in 1996. In 1997 she moved back to Britain to take a University Lecturer position in the Department of Anatomy at Cambridge University. She is currently a Reader in Developmental Neurobiology at Cambridge. In addition to her research and teaching duties, Dr. Holt is on the Editorial Boards of the Journal of Neurobiology and the Journal of Neuroscience. Because of her outstanding research and her excellent speaking ability, she has been invited to present a number of special lectures, including the Schuetze Memorial Lecture at Columbia and the Pfizer Lecture of the Society for Neurosciences.

 

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Photo of Ronald D.G. McKay, Ph.D., Senior Investigator

 

For more information about Dr. Holt  and her research, click here.


Contact Information:

For more information about Neuroscience Day 2004, contact the Neuroscience Program by :

phone: 1-800-952-5386 (outside Miami, FL) or 305-243-3368 (Miami, FL)

or

email: neurosci@med.miami.edu

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neurosci@med.miami.edu · Phone: 800-952-5386 / 305-243-3368  ·  Fax: 305-243-2970 

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